Stable Isotope-Labeled Peptides
Isotope-labeled peptides are commonly used in proteomics research and peptide metabolic pathway research. Generally, stable isotopes N15 and C13 are used for labeling, and mass analysis instruments such as mass spectrometer, gas chromatograph, and nuclear magnetic resonance are used for measurement.
GenCefe provides custom stable isotope-labeled peptides, which directly introduces amino acids labeled with isotopes, such as C, N, during the peptide synthesis process to achieve the purpose of labeling the entire peptide chain. Commonly used isotope-labeled amino acids include alanine (Ala), lysine (Lys), arginine (Arg), etc.
Service Types
N15-labeled isotope peptides
C13-labeled isotope peptides
N15, C13 dual-labeled isotope peptides
Case Studies
[D10]Leu-Insulin (Human) (+40 Da)
[13C18,15N3]-Hepcidin (Human) (+21 Da)
Isotope Types
Amino acid | Code | Mass difference | Isotope | Isotopic enrichment |
Alanine | A | +4 Da | U-13C3, 15N | >99% |
Arginine | R | +10 Da | U-13C6, 15N4 | >99% |
Isoleucine | I | +7 Da | U-13C6, 15N | >99% |
Leucine | L | +7 Da | U-13C6, 15N4 | >99% |
Lysine | K | +8 Da | U-13C6, 15N2 | >99% |
Phenylalanine | F | +10 Da | U-13C9, 15N | >99% |
Proline | P | +6 Da | U-13C5, 15N | >99% |
Valine | V | +6 Da | U-13C5, 15N | >99% |
