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The synthetic DNA library is a combination of a large number of DNA mutant sequences constructed to screen mutant proteins with specific functions. It has been widely used in research fields such as protein directed evolution and antibody screening. GenCefe Biotech's experienced R&D and production team relies on the advanced AI bioinformatics platform and gene synthesis technology platform to provide customized synthetic DNA library services. We can mutate the amino acid or nucleotide sequences specified by customers, or design and synthesize mutation libraries according to customer requirements, such as site-directed mutagenesis libraries, random mutant libraries, degenerate mutation libraries, controlled libraries, sgRNA libraries and other types of library construction services.
Service Features:
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Advanced technology platform: Experienced R&D and production teams, leading bioinformatics and gene synthesis technology platforms, provide you with high-quality library design and synthesis services;
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Comprehensive library types: site-directed mutagenesis libraries, random mutant libraries, degenerate mutation libraries, controlled libraries, sgRNA libraries and other types of library construction services;
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Professional technical support: provide considerate pre-sales technical consultation and after-sales service, and timely update project progress.
Our Services:
| Library Type | Recommended Applications | Details |
| Site-directed mutagenesis libraries |
1. Research on protein structure and function
2. Study of the enzyme active sites 3. Study on the antibodies binding domains 4. Protein property modifications, such as changing thermal stability, substrate binding specificity, etc. |
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| Random mutant library |
1. Research on protein structural functional domains;
2. Antibody humanization; 3. Protein property modifications, such as the determination of the catalytic domain of the enzyme, the improvement of catalytic properties, etc. |
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| Degenerate mutation libraries |
1. Research on protein structural functional domains;
2. Directed evolution of proteins, enzymes, antibodies; 3. Determination and modification of key amino acids in enzyme active sites; 4. Antibody humanization, fine-tuning of antibody affinity and binding properties. |
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| Controlled libraries |
1. Directed evolution of proteins, enzymes, antibodies;
2. New drug target screening; 3. In-depth study of the effect of a few amino acids around the catalytic site of the enzyme on the catalytic properties of the enzyme, etc. |
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| sgRNA Libraries |
1. Large-scale gene knockout, activation and suppression
2. Identification and verification of new drug targets 3. Identify cancer treatment targets 4. Applications in agricultural field, such as development of disease-resistant crops |
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| REQUEST A QUOTE | ||
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| PHONE | ONLINE FORM | |
| [email protected] | +1 408-828-0438 | ONLINE QUOTE SUBMISSION |
