News & Events
14
January 2025

siRNA (small interfering RNA) is a powerful tool for gene silencing, and it has a wide range of applications in both research and therapeutic contexts. Here are the key applications: 

9
January 2025

siRNA (small interfering RNA) and sgRNA (single guide RNA) are both short RNA molecules involved in RNA-mediated gene silencing, but they function in different RNA interference pathways and have distinct roles. Here are the key differences:

7
January 2025

Assessing the silencing effect of siRNA is crucial to confirm its effectiveness in downregulating target gene expression. Several methods can be used to evaluate the silencing efficiency of siRNA. Below are the most common approaches: 

2
January 2025

Designing effective siRNA involves several important factors to ensure high silencing efficiency, specificity, and minimal off-target effects. Below are the key considerations when designing siRNA: 

31
December 2024

Yes, several RNA-based therapeutics using GalNAc conjugation have been approved for clinical use, particularly for liver-targeted therapies. Some of the approved drugs that utilize GalNAc for targeted delivery include: 

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