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Antisense oligonucleotide (ASO) drugs have advanced significantly, establishing themselves as a versatile and effective platform for treating genetic and other complex diseases. Key progress includes the following:
MicroRNA (miRNA) and small interfering RNA (siRNA) are both short, non-coding RNA molecules involved in post-transcriptional gene regulation. Despite their similarities, they differ in origin, mechanism, and application.
MicroRNA (miRNA) therapeutics are being actively developed, with several candidates progressing to clinical and preclinical stages. Below are examples from each category:
MicroRNA (miRNA) therapeutics are being actively developed, with several candidates progressing to clinical and preclinical stages. Below are examples from each category:
Despite progress, miRNA therapeutics faces several challenges that need to be addressed for clinical success.
