The principle of FISH (Fluorescence in Situ Hybridization) probe is to use fluorescently labeled short nucleic acid fragments (DNA or RNA probes) to form a stable hybrid structure with specific nucleic acid sequences in the target sample through base pairing. During the experiment, the DNA or RNA in the sample is first denatured into a single strand, and then the probe binds to the target sequence. The fluorescent signal carried by the bound probe can be directly observed under a fluorescence microscope, thereby achieving precise positioning and quantitative analysis of the target gene or chromosome. This technology is widely used in gene expression research, chromosome abnormality detection and cancer diagnosis. 

GenCefe Biotech's experienced team provides you with professional FISH probe design and synthesis services. We can customize synthetic FISH probes or mixed FISH probe sets according to your needs to improve your research efficiency. A variety of fluorescent labels are available, including Cy3, Cy5, FAM, etc. The delivered FISH probes are all purified by HPLC to ensure purity and quality.

Service Advantages:

     ●      Professional design: Accurately

match the target sequence, improve specificity, and reduce background signal
interference. Mixed FISH probe sets are available.

     ●      High-quality synthesis: The delivered FISH probes are purified by HPLC to ensure product quality.

     ●      Multiple fluorescent labels: Provide Cy3, Cy5, FAM and other conventional dyes. Different fluorescent dyes can be selected according to the customer's multiple detection needs to distinguish the signals of multiple targets.

     ●      Compatibility: Applicable to various sample types such as cells and tissue sections.

Service Specifications:

	Size	Purification Method	Turnaround Time	Order
Mixed Probe Set*	2 OD × 4	HPLC	5 days	Get a quote
DNA Probe Design and Synthesis	Starting from 2 OD	HPLC	Starting from 5 days	Get a quote

* Multiple probes in the Mixed FISH Probe Set are recommended to be mixed to achieve ideal experimental results. If the Mixed FISH Probe Set you ordered is invalid, please provide the experimental data to apply for after-sales service. For qualified after-sales applications, we will redesign and synthesize a set of FISH probes for free.